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James P Zacny Selected Research

Miosis

1/2015Methylnaltrexone: its pharmacological effects alone and effects on morphine in healthy volunteers.
4/2009Within-subject comparison of the psychopharmacological profiles of oral hydrocodone and oxycodone combination products in non-drug-abusing volunteers.
5/2008Subjective, psychomotor, and physiological effects profile of hydrocodone/acetaminophen and oxycodone/acetaminophen combination products.
1/2008Within-subject comparison of the psychopharmacological profiles of oral oxycodone and oral morphine in non-drug-abusing volunteers.
11/2005Profiling the subjective, psychomotor, and physiological effects of tramadol in recreational drug users.
2/2004Characterizing the subjective, psychomotor, and physiological effects of oral propoxyphene in non-drug-abusing volunteers.
11/2003Characterizing the subjective, psychomotor, and physiological effects of oral oxycodone in non-drug-abusing volunteers.
1/2003Characterizing the subjective, psychomotor, and physiological effects of a hydrocodone combination product (Hycodan) in non-drug-abusing volunteers.

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James P Zacny Research Topics

Disease

9Pain (Aches)
11/2013 - 01/2003
8Miosis
01/2015 - 01/2003
7Psychomotor Disorders
01/2012 - 01/2003
2Neoplasms (Cancer)
01/2019 - 01/2016
2Chronic Pain
01/2012 - 01/2012
2Exotropia (Exophoria)
11/2003 - 01/2003
1Thrombocytopenia (Thrombopenia)
01/2019
1Abdominal Pain (Pain, Abdominal)
01/2019
1Mucositis
01/2019
1Breast Neoplasms (Breast Cancer)
01/2016
1Carcinogenesis
01/2016
1Triple Negative Breast Neoplasms
01/2016
1Basal Cell Nevus Syndrome (Gorlin Syndrome)
03/2015
1Constipation
01/2015
1Opioid-Induced Constipation
01/2015
1Nausea
04/2013
1Respiratory Insufficiency (Respiratory Failure)
12/2012
1Fibromyalgia (Fibrositis)
01/2012
1Spasm (Spasms)
11/2011
1Opioid-Related Disorders (Opiate Addiction)
04/2011
1Anxiety Disorders (Anxiety Disorder)
04/2011
1Cough
01/2003

Drug/Important Bio-Agent (IBA)

11Opioid Analgesics (Opioids)IBA
01/2015 - 01/2003
9Pharmaceutical PreparationsIBA
01/2015 - 01/2003
6Oxycodone (Oxycontin)FDA LinkGeneric
04/2013 - 11/2003
5Morphine (MS Contin)FDA LinkGeneric
01/2015 - 01/2003
3Lorazepam (Ativan)FDA LinkGeneric
11/2005 - 01/2003
2Carisoprodol (Soma)FDA LinkGeneric
01/2012 - 11/2011
2Opiate AlkaloidsIBA
04/2009 - 01/2008
2Hydrocodone (Dihydrocodeinone)FDA LinkGeneric
05/2008 - 01/2003
1pazopanibFDA Link
01/2019
1Transaminases (Aminotransferases)IBA
01/2019
1MLN 8237IBA
01/2019
1Aurora Kinase AIBA
01/2019
1ErbB Receptors (EGF Receptor)IBA
01/2016
1human ERBB2 proteinIBA
01/2016
1Forkhead Box Protein M1IBA
01/2016
1Phenobarbital (Luminal)FDA Link
01/2016
1Estrogen ReceptorsIBA
01/2016
1Transcription Factors (Transcription Factor)IBA
01/2016
1Biomarkers (Surrogate Marker)IBA
01/2016
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2016
1HhAntag691IBA
03/2015
1methylnaltrexoneFDA Link
01/2015
1mu Opioid Receptors (mu Opioid Receptor)IBA
01/2015
1Analgesics (Analgesic Drugs)IBA
11/2013
1Neuromuscular Agents (Skeletal Muscle Relaxants)IBA
01/2012
1Pregabalin (Lyrica)FDA Link
01/2012
1Anticonvulsants (Antiepileptic Drugs)IBA
01/2012
1Acetaminophen (Paracetamol)FDA LinkGeneric
05/2008
1oxycodone-acetaminophen (Percocet)FDA LinkGeneric
05/2008
1Sevoflurane (Ultane)FDA LinkGeneric
04/2008
1MioticsIBA
11/2005
1Illicit Drugs (Recreational Drugs)IBA
11/2005
1Tramadol (K315)FDA LinkGeneric
11/2005
1Dextropropoxyphene (Darvon)FDA LinkGeneric
02/2004
1homatropineIBA
01/2003

Therapy/Procedure

3Therapeutics
01/2019 - 01/2012
2Analgesia
01/2008 - 08/2004
1Palliative Care (Palliative Therapy)
01/2015